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Lin Wenjuan
Tel:  86-10-64853723
Fax:  86-10-64872070
Mailing Address:  16 Lincui Road, Chaoyang District, Beijing 100101, China
Email:  linwj@psych.ac.cn
1965-1985      Assistant Research Fellow, Institute of Psychology, Chinese Academy of Sciences
1985           Visiting Research Fellow, La Trobe University, Australia
1986           Associate Professor, Institute of Psychology, Chinese Academy of Sciences
1986-1990,     PhD student, Department of Psychology, La Trobe University, Australia
1990-1992      Senior Associate Research Fellow, Newcastle University, Australia
1993- Present  Professor, Institute of Psychology, Chinese Academy of Sciences
1999           Senior Visiting Research Fellow, Center for Human Growth and Development, University
               of Michigan, USA
Research Interests:
Biopsychology; Psychoneuroimmunology; Health Psychology
Community service:
Membership, New York Academy of Sciences, USA
Membership, The Academy of Sciences for the Developing World
Membership, Australia Psychological Society
Membership, Chinese psychological Society
Associate Membership, East-West Centre, USA
Scholarship for Research from La Trobe University, Australia from 1986-1989
Second Price for Natural Sciences from the Chinese Academy of Sciences in 1998
Outstanding Scientist for Anti-SARS Research in 2003
Excellent Professor from Graduate University of Chinese Academy of Sciences in 2006
Outstanding Professor from Graduate School of Chinese Academy of Sciences in 2008
Selected Publications:

Published more than160 scientific papers on the research of Biopsychology and Psychoneuroimmunology and obtained 3 invention patents. The following are the selective publications and patent.
 Corresponding Author *

1.Juntao Zhang,Wenjuan Lin*, Mingming Tang , Yawei Zhao, Ke Zhang , Xiaqing Wang , Yingcong Li. Inhibition of JNK Ameliorates Depressive-Like Behaviors and Reduces the Activation of Pro- Inflammatory Cytokines and the Phosphorylation of Glucocorticoid Receptors at Serine 246 Induced by Neuroinflammation. Psychoneuroendocrinology, 2020,113, 104580. doi: 10.1016/j.psyneuen.2019.104580

2.Ke Zhang, Wenjuan Lin*, Juntao Zhang, Yawei Zhao, Xiaqing Wang, Mei Zhao*. Effect of Toll-like receptor 4 on depressive-like behaviors induced by chronic social defeat stress. Brain and Behavior, 2020 Mar;10 (3):e01525. doi: 10.1002/brb3.1525.

3.Ming-ming Tang,Wen-juan Lin*, Yu-qin Pan, Ying-cong Li. Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression. Front Cell Neurosci.2018, 8;12: 255. doi: 10.3389/fncel.2018.00255.
4.Ya-wei Zhao, Yu-qin Pan, Ming-ming Tang and Wen-juan Lin*. Blocking p38 Signaling Reduces the Activation of Pro-inflammatory Cytokines and the Phosphorylation of p38 in the Habenula and Reverses Depressive-Like Behaviors Induced by Neuroinflammation. Front Pharmacol. 2018, 15;9: 511. doi: 10.3389/fphar. 2018.00511
5. Ming-ming Tang ,Wen-juan Lin*, Jun-tao Zhang, Ya-wei Zhao, Ying-cong Li . Exogenous FGF2 reverses depressive-like behaviors and restores the suppressed FGF2-ERK1/2 signaling and the impaired hippocampal neurogenesis induced by neuroinflammation. Brain, Behavior and Immunity 2017, 66: 322-331
6. Ming-ming Tang, Wen-juan Lin*, Yu-qin Pan, Xi-ting Guan, Ying-cong Li (2016). Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression. Physiology & Behavior, 161: 166-173.
7. Guan Xiting, Lin Wenjuan*, Tang minmin. Comparison of stress-induced and LPS-induced depressive-like behaviours and the alterations of central pro-inflammatory cytokines mRNA in rats. PsyCh Journal 2015, 2015; 4(3): 113-122
8. Huanhuan Li, Wenjuan Lin*, Junfa Li, Weiwen Wang. Altered Neurogranin Phosphorylation and Protein Levels are Associated with Anxiety- and Depression-Like Behaviors in Rats Following Forced Swim Stress Journal of Behavioral and Brain Science, 2014, 4: 506-522
9. Yuqin Pan , Wenjuan Lin*, Weiwen Wang, Xiaoli Qi , Donglin Wang, MimmmTang. :The effects of central pro-and anti-inflammatory immune challenges on depressive-like behavior induced by chronic forced swim stress in rats. Behavioural Brain Research. 2013, 247: 232-240
10. Wang Donglin, Lin Wenjuan*, Pan, Yuqin Kuang Xueying, Qi Xiaoli, Sun Han: Chronic blockade of glucocorticoid receptor by RU486 enhances lipopolysaccharide-induced depressive-like behavior and cytokine production in rats. Brain, Behavior, and Immunity, 2011  25(4): 706-714
11. Xiaoli Qi, Wenjuan Lin*, Donglin Wang, Yuqin Pan, Meng Sun, Weiwen Wang: A role for the extracellular signal-regulated kinase signal pathway in depression. Behavioral Brain Research 2009, 199 : 203–209
12. Xiaoli Qi, Wenjuan Lin*, Junfa Li, Huanhuan Li, Weiwen Wan, Donlin Wang, Men Sun:  Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiology of Disease, 2008,31(2):178-285
13. Wenjuan Lin*: The involvement of psychological processes in immunocompetence.. Progress in Psychological Science Around the World .2006,159-166. Psychology Press, England
14. Xiaoli Qi, Wenjuan Lin* , Junfa Li, Yuqin Pan, Weiwen Wang:The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress. Behavioral Brain Research 2006 ,175 : 233–240
15. Jihuan Chen, Wenjuan Lin*, Weiwen Wang, Feng Shao, Jie Yang, Bairen Wang, Fang Kuang, Xiaol Duani and Gong Ju: Enhancement of antibody production and expression of c-Fos in the insular cotex in response to a conditioned stimulus after a single-trial learning paradigm. Behavioural Brain Research, 2004,154 (2): 557-565.
16. Jingxin Huang, Wenjuan Lin*,  Jihuan Chen : Antibody response can be conditioned using electroacupuncture as conditioned stimulus. Neuroreport.,2004,15 (9):1475-1478
17. Feng Shao, Wenjuan Lin*, Wang Weiwen, Washinton Jr WC and Li Zheng: The effect of emotional stress on the primary humoral immunity of rats. Journal of Psychopharmacology, 2003, 17(2):153-157
18. Wenjuan Lin*, Nan Sui: Biopsychology research in China. International Journal of Psychology, 2003, 38 (5): 311-322.
19.Singer G, Lin Wenjuan: Psychology tomorrow.  The bulletin of the Australian Psychological Society, 12, 1995, 1-4
18.. Wenjuan Lin,, George Singer,Dan Irby: Effect of hypophysectomy and corticosterone implantation on schedule-induced wheelrunning.. Pharmacology Biochemistry and Behavior, 1990, 35: 739-742
20. Wenjuan Lin, George Singer, John Funder: The action of corticosterone on schedule-induced wheel running.  European Journal of Pharmacology, 1989, 171: 9-15
21. Wenjuan Lin, George Singer ,Micheal Papasava: The role of adrenal corticosterone in schedule-induced wheel running.  Pharnacology Biochemistry and Behavior, 1988, 30: 101-10

Principal Investigator for many research projects supported mainly by the grants from the National Science Foundation of China (NSFC) and the grants from the Chinese Academy of Sciences.
The following are the currently running projects supported by the grants from the NSFC:
1. The role of cytokines in the stress-induced depressive behavior in rats
2. The role of the ERK-CREB signal system in the stress -induced depressive behavior in rats
3. Role of inflammatory and anti-inflammatory cytokines in the pathophysiology of depression